a 2013 study by the Amino Acids scholarly journal summarizes how metabolic disorders are mitigated through the appropriate glycine dosage, which include those individuals suffering from obesity; cardiovascular disease; ischemia reperfusion injuries; a number of inflammatory diseases; cancers; diabetes;
additionally, a 2011 study conducted by Bannai and Kanai from the Journal of Pharmacological Studies found that quality sleep and a reduction in mental anxiety can occur by taking up to 3 grams of glycine an hour prior to sleep, an alternative to the occasional fatigue-inducing melatonin


Food and Beverage:

serving as a sweetener and taste enhancer, there are various food supplements and protein drinks containing glycine that can be purchased for consumption;
pets, in addition to humans, also ingest glycine as it is a common food additive for dogs, cats and other animals

Pharmaceutical and Cosmetics:

intravenous injection of glycine may be appropriate for certain individuals with a urologic condition, but caution must be used in regards to appropriate dosage;
glycine is added in conjunction with certain drugs in order to increase gastric absorption;
furthermore, glycine’s practical uses include being a buffering agent (minimizing the change in a product’s pH) for antiperspirants, cosmetics, analgesics, toiletries and antacids


L-Glycine (or simply Glycine) is a non-essential amino acid that can be produced from other chemicals, including the amino acids, Serine and Threonine. However, if already deficient in Serine levels, a non-essential amino acid itself, an increase in high-protein foods such as fish, eggs and legumes may be the best option to take. Structurally, glycine is the simplest type of amino acid as its side group contains only a single hydrogen atom, giving it the ability to fit in both hydrophilic and hydrophobic environments and having a very high solubility in water (between a fourth and third of glucose’s water solubility under room temperature).

Collagen is a protein that is a critical structural component of the skin, muscle and bone of animals (including humans) and is more than one-third glycine in its composition. It is suggested that at least 10 grams of collagen synthesis is needed on a daily basis and as glycine is collagen’s central component, the expected daily synthesis of 3 grams of glycine from one’s own body doesn’t seem to be enough. Therefore, it is reasonable to suggest substituting “semi-essential” for “non-essential” when labelling glycine.


Glycine was one of the first amino acids to be isolated from Gelatin in the early 19th century and is well-known for its sweet taste, which explains its modern use as a sweetener or taste enhancer. In fact, its discovery in 1820 was by Henri Braconnot, a French chemist and pharmacist. The product, glycine, was the result of Henri’s boiling of a gelatinous object with sulfuric acid.

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